Abstract Background Hibernation is a physiological state exploited by many animals exposed to prolonged adverse environmental conditions associated with winter.Large changes in metabolism and cellular function occur, with many stress response pathways modulated to tolerate physiological challenges that might otherwise be lethal.Many studies have so
Effect of technological methods on the formation of seed productivity of a Lotus corniculatus in the Udmurt Republic
Lotus corniculatus - valuable bean fodder crop, the main advantages of which are its long life, high resistance to trampling, nutritional value, the ability to grow on acidic soils.However, the spread of a lotus on the territory of the Udmurt Republic is dozy dinkum moppet restrained due to the complexity of its seed production, which is due to the
Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
Summary: Hepatocytes are the primary functional cells of the liver, performing its metabolic, detoxification, and endocrine functions.Functional hepatocytes are extremely valuable in drug discovery and evaluation, as well as in cell navy blue lantern therapy for liver diseases.However, it has been a long-standing challenge to maintain the functions
Extra-gastrointestinal stromal tumor arising in the lesser omentum with a platelet-derived growth factor receptor alpha (PDGFRA) mutation: a case report and literature review
Abstract Background Gastrointestinal stromal tumors (GIST) arising from sites other than the gastrointestinal (GI) tract, termed extra-gastrointestinal stromal tumors (EGIST), are rare.Among EGIST, those with platelet-derived growth factor receptor alpha (PDGFRA) mutations are even rarer, with only a few cases reported.About 80% of GIST has KIT mut